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Klebsiella outbreak

Klebsiella outbreak

The eradication and prevention of Gram-negative rods (GNRs) including Klebsiella in the healthcare environment is becoming an increasing and more pressing priority for hospital managers and infection control teams.

The control of Gram-negatives is complex due to the fact that most are catalase-positive. Catalase is an enzyme which can break down hydrogen peroxide. Bioquell hydrogen peroxide vapour (HPV) technology is the only HPV technology which is proven to be able to overcome catalase-positive microorganisms

Whether you are concerned about the efficacy or the time taken for your disinfection process, Bioquell is able to offer a tailor-made programme that can eliminate GNR's from single rooms in less than two hours (depending on room size/conditions).

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Our Solutions

Whether a hospital is experiencing an outbreak of Klebsiella or endemic GNR issues, Bioquell's Gram-negative Eradication Programme will maximise the benefits from Bioquell's technology, whilst minimising the operational challenges to the hospital.

Each programme can be tailored to meet hospital specific needs.

For more information on Klebsiella, visit the Klebsiella microbiology section.

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Benefits

  • Bioquell is the only HPV technology which is able to overcome catalase-positive micro-organisms including Klebsiella and can totally eradicate Gram-negative pathogens from the environment. It is verified by inactivation of 6-log Geobacillus stearothermophilus biological indicators, the same method used to validate steam sterilisers/autoclaves
     
  • Bioquell offers a tailor-made service with the ability to eliminate GNRs from single rooms in less than 2 hours*. This is far quicker than stringent cleaning protocols allowinf for faster room turnaround
     
  • Entire unit bio-decontamination can be carried out in less than 12 hours and has the added benefit of decontaminating common areas (e.g. nursing stations)
     
  • By reducing cleaning downtime and preventing bed-blocking by patients infected with GNRs, Bioquell's Gram-negative eradication programme can increase the number of patients treated per year, generating significant cost benefits
     
  • Full reporting, designed to assist the hospitals management and support regulatory requirements
     
  • Extensive worldwide experience, with over 100 successful Bioquell Outbreak Emergency deployments
     

* depending on room size and starting environmental conditions

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FAQs

 
What evidence is there that Bioquell can suppress the spread of Gram-negatives?

Bioquell has been used to control several outbreaks of Gram-negatives around the world. Many of these remain unpublished but several have been published, for example, an outbreak of Acinetobacter and Enterobacter on an ICU in the Netherlands (Otter JA, Yezli S, Schouten MA, van Zanten AR, Houmes-Zielman G, Nohlmans-Paulssen MK. Hydrogen peroxide vapor decontamination of an intensive care unit to remove environmental reservoirs of multidrug-resistant gram-negative rods during an outbreak. Am J Infect Control 2010; 38: 754-756); an outbreak of Serratia marcescens on a neonatal ICU in Sheffield (Bates CJ, Pearse R. Use of hydrogen peroxide vapour for environmental control during a Serratia outbreak in a neonatal intensive care unit. J Hosp Infect 2005; 61: 364-366.); and an outbreak of A. baumannii in an ICU in the USA (Donnegan N, Croxton M, Jones M, Farrare-Wilmore P, Geiser K, Pic-Aluas L. Vaporized Hydrogen Peroxide as Part of a Control Intervention during an Outbreak of Acinetobacter in an ICU. Society for Healthcare Epidemiologists of America Annual Meeting, 2010, Abstract 207). The control of multidrug-resistant Gram-negatives is crucially important in light of the emergence and spread of carbapenemases such as NDM-1 and KPC-2.

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